Hormone Replacement Therapy (HRT)
Hormone replacement therapy can help restore hormone levels when symptoms of hormone decline affect energy, mood, sleep, weight, and sexual health. At the Center for Antiaging Aesthetic and Rejuvenation Medicine PLLC, renowned bioidentical hormone specialist Yale (Yoel) R. Smith, MD uses detailed evaluation and lab analysis to determine what your body needs—safely and strategically.
Evidence-informed, individualized hormone care
Hormone therapy decisions should be personalized—based on symptoms, medical history, and risk factors— with ongoing monitoring and follow-up. Sources: Mayo Clinic, The Menopause Society (NAMS) Position Statements
- Bioidentical hormones are lab-made and designed to mimic human hormones; safety varies by formulation and should be clinician-guided. Source: Cleveland Clinic
- Testosterone therapy should only be used when low testosterone is confirmed and requires appropriate monitoring. Sources: Endocrine Society, AUA
- Menopausal hormone therapy can be effective for hot flashes and vaginal symptoms; risks/benefits depend on timing and individual factors. Source: Mayo Clinic
What is hormone replacement therapy?
Hormone replacement therapy helps restore hormone levels when you’re experiencing symptoms related to hormone decline or imbalance. Dr. Smith may prescribe bioidentical hormone therapy—formulations designed to match the molecular structure of hormones naturally produced in the body—when clinically appropriate.
HRT delivery options may include
- Oral medications
- Patches
- Skin creams
- Skin gels
- Suppositories
How testing and evaluation work
Dr. Smith uses a detailed history, symptom review, and lab testing (often including blood and/or saliva analysis) to evaluate your needs and reduce risk. For a controlled substance like testosterone, labs and testing must be retaken every 90 days.
In many cases, hormone optimization can be combined with other strategies—such as nutrition, nutraceutical support, and other longevity-focused approaches—based on your goals and findings.
When should you consider hormone replacement therapy?
Many people consider HRT when hormone-related symptoms begin to affect daily life—energy, sleep, mood, weight, and sexual health. Women often notice a more significant shift around menopause, while men may experience more gradual changes and may benefit from evaluation when symptoms suggest low testosterone or other imbalances.
Common symptoms that prompt evaluation
- Lack of energy
- Low libido
- Weight gain
- Hair thinning
- Loss of muscle mass
- Brain fog
- Mood swings or depression
- Sleep problems
- Hot flashes / night sweats
- Vaginal dryness (women)
- Erectile dysfunction (men)
Why timing and monitoring matter
Hormone therapy can be beneficial for specific symptoms, but suitability depends on your health history and risk profile. Monitoring and follow-up are essential.
Testosterone therapy specifically should be considered only after confirming low testosterone with appropriate evaluation and with a monitoring plan.
Frequently Asked Questions
Clear answers with references to trusted medical organizations.
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Your visit focuses on symptoms, history, goals, and lab-driven evaluation. We’ll discuss options and a personalized plan with ongoing monitoring.
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