Wellness Testing • Food Reactivity Insights

Cyrex® Food Sensitivities & Immune Reactivity Testing

A structured, clinician-guided approach to exploring food-related immune patterns.

If you experience persistent digestive discomfort, skin flares, headaches, joint aches, or “mystery symptoms” after meals, you may be wondering whether foods are playing a role. Cyrex panels are designed to measure immune reactivity to a broad range of food antigens (often reported as IgG/IgA reactivity), which can be used alongside your history and symptoms to guide a more targeted plan.

Food allergy vs. intolerance vs. “sensitivity”

Food reactions are common, but not all reactions are true allergies. A true food allergy involves the immune system (often IgE) and can be serious; intolerances are typically non-immune digestive reactions. Sorting this out matters for safety and clarity.

  • Food allergy is an immune response and can be life-threatening (anaphylaxis). MedlinePlus (NIH)
  • Most food reactions are intolerances rather than allergies. Mayo Clinic
  • IgG “food panels” are not recommended to diagnose allergy or intolerance. AAAAI
What this page covers

What Cyrex Food Reactivity Testing Can (and Can’t) Do

Cyrex offers panels that assess immune reactivity to many real-world food antigens (often including cooked, raw, and processed forms) and may be used to help clinicians structure elimination/reintroduction strategies and monitor response over time. For example, Cyrex describes Array 10 / 10–90 as a multiple-food immune reactivity screen measuring reactivity to a large number of food antigens on one panel. (Cyrex Array 10)

Important:

Major allergy organizations caution that IgG food testing should not be used to diagnose food allergy or food intolerance/sensitivity. Results can reflect exposure or tolerance rather than a harmful reaction. If you have symptoms of a true allergy (hives, swelling, breathing difficulty, anaphylaxis), you should seek allergy evaluation and use validated allergy testing as clinically appropriate. (AAAAI; CSACI Position Statement)

Credible references used on this page: Mayo ClinicMedlinePlus (NIH)AAAAICSACI (open access)Cyrex Array 10

When patients often ask about food reactivity

  • Ongoing bloating, gas, abdominal discomfort, or irregular bowel habits
  • Skin symptoms that seem food-related (eczema-like flares, rashes)
  • Headaches, fatigue, “brain fog,” or joint aches after meals
  • Symptoms that persist despite “eating healthy”
  • Complex or multi-system symptom patterns where structure and clarity are needed
If you have red-flag allergy symptoms (swelling, wheezing, throat tightness, severe hives), seek urgent medical care and allergy evaluation. (MedlinePlus/NIH)

How a clinician-guided process typically works

  • Step 1: Review symptoms, diet patterns, timing, and health history
  • Step 2: Choose appropriate testing (when clinically helpful)
  • Step 3: Build a focused plan (often an elimination + reintroduction strategy)
  • Step 4: Track outcomes and adjust (symptoms, labs, nutrition adequacy)
  • Step 5: Long-term maintenance with the least restrictive plan possible
Broad elimination diets without supervision can be unnecessarily restrictive. We aim for precision and reintroduction when appropriate.

Which Cyrex panels are commonly discussed?

Your clinician may recommend different panels depending on symptoms and history. Examples Cyrex describes include:

Array 10 / 10–90 (Multiple Food Immune Reactivity Screen)

Cyrex describes Array 10 / 10–90 as a multi-food immune reactivity panel that measures reactivity to many real-world food antigens, including cooked, raw, and modified/processed forms, on one panel.

Source: Cyrex Array 10

Optional add-ons (based on symptoms)

Cyrex also describes panels focused on intestinal barrier/antigenic permeability (Array 2) and wheat/gluten proteome reactivity (Array 3X), which some clinicians consider when symptoms or history suggest these areas are relevant.

Frequently Asked Questions

Clear answers with links to trusted medical and professional sources.

Not necessarily. Food allergy is an immune response (often IgE) and can be serious or life-threatening, while many food reactions are intolerances that don’t involve the same immune mechanisms and are typically not life-threatening. Sources: MedlinePlus (NIH)Mayo Clinic
Cyrex describes Array 10 / 10–90 as a “Multiple Food Immune Reactivity Screen” measuring immune reactivity to a large panel of real-world food antigens, including cooked, raw, and processed forms, on one panel. Source: Cyrex Array 10
Major professional organizations caution that IgG food testing should not be used to diagnose food allergy or food intolerance/sensitivity, because IgG can reflect exposure or tolerance rather than a harmful reaction. Results, if used at all, should be interpreted in clinical context. Sources: AAAAICSACI Position Statement
Symptoms like hives, facial/lip swelling, throat tightness, wheezing, severe vomiting, dizziness, or anaphylaxis require prompt medical attention and evaluation for true food allergy. Source: MedlinePlus (NIH)
We typically pair your history and symptoms with a structured nutrition strategy (often an elimination + reintroduction framework), track changes, and aim for the least restrictive long-term plan that supports your health and quality of life. Reference reading (allergy vs intolerance): Mayo Clinic

Request Cyrex Testing

Use the form below to request an appointment or testing discussion. This form is for non-urgent requests only. If this is an emergency, call 911.

What to expect

We’ll review your symptoms, diet patterns, timeline, and goals, then decide whether testing is clinically appropriate and which panel(s) fit best.

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